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DeCS
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Descriptor English:
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Anesthetics, Local
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Descriptor Spanish:
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anestésicos locales
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Descriptor Portuguese:
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Anestésicos Locais
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Synonyms English:
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Anesthetics, Conduction Blocking
Anesthetics, Conduction-Blocking
Anesthetics, Topical
Conduction Blocking Anesthetics
Conduction-Blocking Anesthetics
Local Anesthetics
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Tree Number:
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D27.505.696.277.100.200
D27.505.696.663.850.025
D27.505.954.427.210.100.200
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Definition English:
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Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. |
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Indexing Annotation English:
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see note at ANESTHETICS
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Allowable Qualifiers English:
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Record Number:
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790
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Unique Identifier:
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D000779
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Occurrence in VHL:
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Similar:
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DeCS
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